Hematology Research / Work-In-Progress Seminar

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Speaker Index

Speaker Date Title
Abdul-Nabi, Anmaar Oct 10, 2008 Molecular and Biological Effects of AML-associated Fusion Proteins on Primary Human CD34+ Cells
Abendschein, Dana Apr 17, 2015 Can We Inhibit Thrombosis Without Increasing Bleeding?
Agre, Peter Oct 6, 2022 Stanley J. Korsmeyer Memorial Lecture: Aquaporin Water Channels: From Atomic Structure to Malaria
Ailhaud, Gerard Mar 23, 2001 Early Events and Redundancy in Adipogenesis
Alford, Shannon Sep 14, 2007 Sphingosine 1-phosphate-mediated Endothelial Cell Migration in Human Platelet Poor Plasma
Amend, Sarah Mar 2, 2012 Identification of the Genetic Basis of MGUS and Multiple Myeloma Susceptibility in KaLwRij Mice
Jan 25, 2013 Of Mice and Men: Genetic Contributions of Susceptibility to MGUS, the Requisite Precursor of Multiple Myeloma
Anbukumar, Dhanam Feb 3, 2012 Calcium Binding Studies of von Willebrand Factor Propeptide
Nov 16, 2012 Characterizing VWF Propeptide Ca2+ Binding Sites
Dec 20, 2013 Cation Dependence of vWF Multimerization
Oct 17, 2014 A Calcium Conundrum: The Role of Calcium in VWF Multimerization
Dec 10, 2015 The ATP7A Copper Transporter Is Required for VWF Multimerization
Sep 22, 2016 Copper Transport in Von Willebrand Factor Biosynthesis
Nov 2, 2017 The Involvement of Copper Transport in Von Willebrand Factor Biosynthesis
Mar 21, 2019 The Function of Copper Ions in vWF Multimer Assembly
Anderson, Richard Apr 21, 2006 Phosphoinositide Signaling: From Biochemistry to Human Disease
Anderson, Trish Jan 21, 2005 Work-in-Progress
Mar 30, 2007 ADAMTS13 Structure and Function
Feb 29, 2008 ADAMTS13 Spacer Domain and Substrate Recognition
Dec 12, 2008 Substrate Recognition by the ADAMTS13 Spacer Domain
Dec 11, 2009 More on ADAMTS13 Spacer Domain and VWF Substrate Recognition
Andrews, Nancy Oct 22, 1993 An Erythroid Transcription Factor Regulating Globin Gene Expression and Iron Metabolism
Oct 23, 1998 Iron Deficiency and Iron Overload: Insights From Anemic Animals
Armanios, Mary Jan 31, 2019 The Telomere Syndromes: Implications for Patient Care
Feb 10, 2020 The Telomere Syndromes: A Paradigm for Molecular Medicine
Arora, Vivek Dec 17, 2015 Defining Novel Oncogenic Drug Targets in Bladder Cancer
Ataga, Kenneth Feb 28, 2020 Meeting Unmet Needs in Sickle Cell Disease
Atkinson, John May 18, 2001 Immune Adherence Revisited
Oct 14, 2005 HUS: Not Enough Regulation of Innate Immunity
Apr 6, 2012 Atypical Hemolytic Uremic Syndrome
Baenziger, Jacques May 7, 1999 The Sulfated Oligosaccharides on LH Reveal the Roles Played by Glycosylation During the Reproductive Cycle
Oct 5, 2007 Carbohydrates Determine Hormone Potency in Vivo
Apr 18, 2014 Molecular Multi-Tasking: New Insights Into Hepatic Glycan Receptor Function
Baeten, Jeremy Mar 4, 2021 TP53 in Clonal Hematopoiesis
Mar 3, 2022 Synergistic Lethality of Decitabine and ATR Inhibition in TP53-Mutant AML
Baldo, Guilherme May 13, 2011 Pathogenesis of the Aortic Valve Disease in MPS VII
Bankaitis, Vytas Apr 26, 1996 Phosphatidylinositol Transfer Proteins: a New Class of Intracellular Regulatory Molecules
Dec 5, 2007 A High Resolution Look at a Superfamily of Nanoreactors That Control Phosphoinositide Signaling in Eukaryotic Cells
Baranski, Tom Feb 25, 2000 Genetic Analysis of G Protein Signalling
Nov 7, 2003 Understanding the Receptor Switch: How Do Hormones Activate G Proteins?
Barnes, Terra (with Stuart Kornfeld) Jan 14, 2011 The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering
Bassler, Bonnie L. Sep 22, 2017 9th Rosalind Kornfeld Lecture: Bacterial Quorum Sensing and Its Control
Batista, Luis Mar 21, 2013 Human IPS Cells as a Model to Study Telomere Dysfunction-Induced Disease
May 29, 2015 Generation of an Isogenic Model to Study the Consequences of Telomerase Mutations in Human Stem Cells
Sep 8, 2022 Misconduct
Bednarski, Jeffrey Sep 29, 2016 Physiologic and Genotoxic DNA Damage Activate Distinct Cellular Responses in Developing B Lymphocytes
Beerman, Isabel Mar 8, 2016 Hematopoietic Stem Cell Aging
Berrien-Elliott, Melissa Apr 18, 2019 miR-142 Is Required for NK Cell Homeostasis and Function
Bertina, Rogier Apr 11, 1997 Genetic Analysis of Inherited Thrombophilia
Bessler, Monica Nov 8, 1996 Molecular Basis of Paroxysmal Nocturnal Hemoglobinuria
Oct 17, 1997 A Mouse Model for Paroxysmal Nocturnal Hemoglobinuria: Use of the Cre/LoxP System to Circumvent Embryonic Lethality
Mar 26, 1999 Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria
Nov 3, 2000 PNH: the Human Disease and Animal Models
Nov 1, 2002 Bone Marrow Failure and Telomerase
Jan 14, 2005 Paroxysmal Nocturnal Hemoglobinuria - From Bench to Bedside
Apr 6, 2007 Housekeeping Ain't No Joke! the Importance of Ribosome Biogenesis in Human Blood Disorders
Apr 3, 2009 Towards a New Understanding of Bone Marrow Failure
Bhattacharya, Deepta Feb 7, 2014 Convergent Differentiation During Hematopoiesis
Bigg, Paul Dec 17, 2010 The Pathogenesis of Mitral Valve Disease in Mucopolysaccharidosis VII Dogs
Blumer, Ken May 7, 2004 RGS Proteins: New Regulators of Blood Pressure Homeostasis and G Protein-Mediated Vasoconstrictor Signaling
Bock, Paul Sep 22, 2006 Blood Coagulation Out of Control: Molecular Sexuality Mechanism of Prothrombin Activation by Staphylocoagulase
Bock, Susan Apr 22, 1994 Antithrombin III and Serpin Structure/Function Studies
Boonen, Marielle Oct 2, 2009 Mucolipidosis Type II Mice Accumulate Autophagolysosomes in Fibroblasts and Serous/mucous Type Secretory Cells
Mar 20, 2015 Cathepsin D and Neuronal Differentiation: Lessons From the Identification of a New Binding Partner
Bose, Ron Mar 11, 2011 Kinase Activation and Signaling: How Does the Her2 Tyrosine Kinase Give Rise to Breast Cancer?
Boucher, Paul Mar 11, 2021 Adenoviral Vector Mediated Gene Editing of the B Cell Receptor as an HIV Vaccine
Brachmann, Rainer Oct 9, 1998 Yeast as a Genetic Tool to Study the Tumor Suppressor Protein P53
Sep 28, 2001 Stories of and Around P53
Brakhane, Molly May 5, 2022 Role of Calcium Signaling in Hematopoiesis in MPNs
Brass, Skip May 6, 2011 Dynamic Regulation of Platelet Accumulation Following Vascular Injury
Bray, Paul Oct 10, 2014 Platelet PAR4 Functional Genomics: Racial Disparities in Anti-Platelet Therapy
Mar 31, 2016 Plateletomics: Exploring Platelet Biology Via Multi-omic Data Integration
Bredemeyer, Andrea Oct 15, 2020 Generation of Yolk-Sac-Like and Definitive Macrophages From Human PSCs
Brenner, Kirsten Feb 13, 2015 Regulation of the Telomerase RNA Component TERC in Human Development and Disease
Mar 24, 2016 Telomere-Independent Functions of the Telomerase RNA Component in Human Stem Cells
Oct 20, 2016 Telomere-independent Functions of the Telomerase RNA Component in Human Stem Cells
Oct 12, 2017 A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells
Sep 27, 2018 A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells
Brost, Taylor May 19, 2016 Interrogation of Genetically Distinct Clones Using MPN Patient-Specific IPSCs
Brown, Ric Dec 9, 1994 Signal Transduction by Leukocyte Integrins
Broze, George Oct 4, 1996 Effects of Tissue Factor and Tissue Factor Pathway Inhibitor Gene Deletion
Dec 18, 1998 What About Protein Z?
Oct 20, 2000 Protein Z and Thrombosis
Dec 13, 2002 Regulation of Coagulation by Protein Z
Apr 22, 2005 TFPI α and β
Mar 9, 2007 Protein Z-Dependent Protease Inhibitor
Sep 25, 2009 Regulation of Coagulation
Dec 10, 2010 Tissue Factor Pathway Inhibitor
Feb 15, 2013 Translational Studies of Tissue Factor Inhibitors
Bruchas, Michael Jan 26, 2017 Dissecting Neuromodulatory Circuits in Affective Behavior
Brugge, Joan Mar 18, 2020 Oxidative Stress Defenses in Cancer
Brunelli, Angelo Jan 21, 2021 Pevonedistat Targets Malignant Cells in Myeloproliferative Neoplasms in Vitro and in Vivo Via NFkB Pathway Inhibition
Bu, Guojun Apr 9, 2004 The LDL Receptor Family: What These Receptors Don't Do
Byun, Minji Nov 5, 2015 Searching for the Genetic Etiology of Infectious Diseases
Camargo, Fernando Nov 17, 2016 Clonal Analysis of Native Hematopoiesis
Challen, Grant Dec 13, 2013 The Epigenetics of Hematopoietic Stem Cell Self-Renewal and Transformation
Chan, Andy Mar 4, 1994 Protein Tyrosine Kinases in T Cell Activation: Bench to Bedside
Chang, Sandy May 7, 2010 How Telomeres Repress the DNA Damage Response
Chang, Shao-Chun Sep 10, 2004 The Pathway to Inositol Hexakisphosphate Synthesis
Chavez, Monique Oct 29, 2020 Investigating Lenalidomide Treatment-Based Secondary B-Cell Acute Lymphoblastic Leukemia
Oct 28, 2021 A Mouse Model of Subclonal Gene Mutations in Myelodysplastic Syndrome
Nov 10, 2022 The Contribution of Subclonal Gene Mutations in Myelodysplastic Syndrome Progression
Cheng, Emily Sep 24, 2004 Apoptotic Checkpoints at the Mitochondrion
Dec 14, 2007 Regulation of Cell Death by BCL-2 Family and Beyond
Cherian, Mathew Mar 1, 2013 Role of PI3K-Akt-mTOR in HTLV-Tax Induced Transformation
Apr 25, 2014 Role of the PI3K-Akt mTOR Pathway in Human T Cell Leukemia Induced Transformation
Mar 13, 2015 Role of the PI3K-Akt-mTOR Pathway in HTLV Induced Leukemogenesis
Cheung, Vivian G. Oct 27, 2017 45th Carl Moore Lecture: It's in the RNA: Implications for Human Disease
Chheda, Milan Feb 9, 2017 Developing a Synthetic Lethal Genetic Screen to Identify Vulnerabilities in IDH1 Mutant Gliomas
Chiquetto, Luana Feb 17, 2022 The Role of Stathmin-1 in the Regulation of HSCs
Choi, Jaebok Jan 20, 2012 Interferon Gamma Receptor Signaling and T Cell Trafficking in Graft vs. Host Disease
Choi, Kyunghee Apr 20, 2012 Regulation of Hematopoietic and Vascular Development
Cho, Jaehyung (Gus) Feb 14, 2020 Mechanisms Regulating Intravascular Cell-Cell Interactions in Thrombosis and Inflammation
Christopher, Matt Apr 10, 2015 Cold Shock Domain Proteins in Normal and Malignant Hematopoiesis
Feb 11, 2016 WT1 in Normal and Malignant Hematopoiesis
Clevers, Hans Mar 2, 2016 43rd Carl Moore Lecture: Lgr5 Stem Cell-Grown Organoids and Their Applications
Cocco, Lucio Apr 30, 2010 Nuclear Phospholipase C Beta1 Signalling, MDS and AML: From Bench to Clinics
Cole, Christopher Mar 22, 2013 Role of DNMT3A in Acute Promyelocytic Leukemia
Mar 28, 2014 The Role of Dnmt3a in Acute Promyelocytic Leukemia
Collier, Timothy May 3, 2013 Probing the Structure and Dimerization of EGFR Family Tyrosine Kinases
Collins, Taylor Feb 16, 2017 Utilizing iPSCs as a Model System to Interrogate Genetically Distinct Clones in Myeloproliferative Neoplasms
Oct 5, 2017 Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs
Dec 13, 2018 Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs
Sep 19, 2019 Interrogating the Role of ASXL1 and JAK2 Mutations in MPNs Utilizing Human Pluripotent Stem Cells
Cooper, John Jan 19, 1996 Control of Actin Assembly by Capping Protein
Cordes, Ethan Nov 10, 2022 TGS1 Depletion Increases Telomerase RNA Stability in Dyskeratosis Congenita
Cottrell, Kyle Apr 18, 2019 Upregulation of 5'TOP mRNAs Following Loss of the Tumor Suppressor ARF
Crabtree, Gerald Nov 9, 2012 40th Carl Moore Lecture: Chromatin Regulation: New Methods and Concepts
Creamer, Philip Feb 1, 2018 Investigating Gene Expression During Human Definitive Hematopoietic Specification
Feb 14, 2019 Defining the Role of CDX4 During Human Definitive Hematopoietic Specification
Crowley, Stephanie May 13, 2021 BCLAF1 Regulation of Hematopoietic Stem Cell Repopulating Capacity
Apr 7, 2022 Bclaf1 Promotes Hematopoietic Stem Cell Repopulating Capacity
Cummings, Rick Feb 2, 1996 The Glycobiology of Schistosomiasis: From Molecular Mimicry to Autoimmunity
Dahms, Nancy Feb 27, 1998 Insight Into Lysosomal Enzyme Recognition by the Mannose 6-Phosphate Receptors
Dalla-Favera, Riccardo Oct 10, 2017 Stanley J. Korsmeyer Memorial Lecture: Molecular Genetics of B Cell Lymphoma
Dang, Luke Mar 19, 2010 Two Histidine Residues Required for the pH Dependent Multimerization of Von Willebrand Factor
Das Thakur, Meghna Mar 16, 2007 The Role of LIM Proteins in Cell-Cell Adhesion and Epithelial Polarity
May 16, 2008 Role of the Ajuba LIM Protein in Size Control in Drosophila Epithelia
Davidson, Nick May 30, 2003 RNA Editing: Molecular Mechanisms and Biological Consequences
Day, Ryan Feb 4, 2021 Distinct Profiles of CBF Leukemias
Dean, Doug Feb 16, 1996 Mechanism of Action of the Retinoblastoma Tumor Suppressor
Oct 26, 2001 The Role for Rb in Tumor Suppression
Dege, Carissa May 5, 2016 Characterization of Human Pluripotent Stem Cell Derived Natural Killer Cells
Oct 27, 2016 Generation and Characterization of Human Pluripotent Stem Cell-derived Natural Killer Cells
Oct 12, 2017 Natural Born Killers? Determining Function and Ontological Origins of Two Distinct Natural Killer Cell Populations Derived From Human Pluripotent Stem Cells
Sep 27, 2018 Ontogeny Is a Critical Determinant of Human Pluripotent Stem Cell Derived Natural Killer Cell Function
Oct 3, 2019 Potently Cytotoxic Natural Killer Cell Potential Initially Emerges From Erythro-Myeloid Progenitors During Mammalian Development
Degen, Jay May 10, 1996 Hard Knocks to the Hemostatic Balance: Fibrinogen and Plasminogen Deficiency in Mice
DeNardo, David Sep 6, 2013 Reprogramming Macrophages to Improve Responses to Chemo- and Immunotherapy
DePinho, Ronald Dec 8, 2000 28th Carl Moore Lecture: Telomerase, Tumor Suppressors and Tumorigenesis
Deuel, Tom Mar 29, 1996 Mechanisms of Transcriptional Regulation by the Wilms Tumor Suppressor Gene
Jun 1, 2011 Shaping the Tumor Phenotype and Microenvironment: New Pathways, New Therapeutic Targets
DeWeerd, Rachel Mar 18, 2021 The Experimentally-Defined APOBEC3A Signature Is Prevalent in Human Cancers
Di Cera, Enrico Feb 13, 1998 Thrombin Allostery
Oct 8, 2004 Rational Design of a Thrombin Mutant With Potent and Safe Anticoagulant/Antithrombotic Activity in Vivo
Diacovo, Tom Dec 10, 1999 Platelets and the Molecular and Cellular Interactions Governing Their Adhesion: From Arterial Injury to Venular Inflammation
Dick, John Nov 19, 1993 Modeling Normal and Leukemic Hematopoiesis in SCID Mice
Dietz, Hal Nov 19, 2010 38th Carl Moore Lecture: TGFβ in the Pathogenesis and Prevention of Aneurysm: Embracing Paradox
Dinauer, Mary Mar 9, 2012 Getting a License to Kill: Regulation of the Leukocyte NADPH Oxidase
DiPaola, Jorge Jan 7, 2019 Studying Megakaryocytes, From Inherited Disorders to Old Age Platelets
DiPersio, John Dec 19, 1997 Cytokine Signaling Pathways
Dolatshahi, Leili Feb 22, 2013 Adjuvant Low Dose Rituximab for Patients with TTP
Doray, Balraj Jan 7, 2005 Work-in-Progress
Mar 3, 2006 Work-in-Progress
Feb 2, 2007 The α/σ2 Hemicomplex of Clathrin Adaptor AP-2 Harbors the Dileucine Recognition Site
Oct 26, 2007 Identification of Acidic-dileucine Signals That Bind to GGAs and AP-1/AP-2
Feb 13, 2009 Understanding the GGA Null Phenotype
Dec 11, 2009 Characterization of Mouse GGA2 Antibodies
Mar 4, 2011 GGA Autoinhibition Re-revisited: Do Internal Dileucines Bind GGA VHS Domains
Feb 17, 2012 GGA Null Mice: The Final Chapter? Or Not?
Jan 11, 2013 Gga2 Knockout Mice Revisited
Dec 20, 2013 Influence of Genetic Background on Lethality of GGA2 Knockout Mice
Nov 14, 2014 Assembly of UDP-GlcNAc-1-Phosphotransferase, a Multi-Subunit Protein
Sep 10, 2015 Understanding How GlcNAc-1-Phosphotransferase Recognizes Lysosomal Enzymes: Part I
Nov 4, 2021 Insight Into Regulation of GlcNAc-1-Phosphotransferase Function as Revealed Through Cryo-EM Analysis
Doudna, Jennifer Nov 13, 2015 8th Rosalind Kornfeld Lecture: The CRISPR-Cas9 Genome Engineering Revolution
Druker, Brian Mar 3, 2000 CML and STI 571: Validating the Promise of Molecularly Targeted Therapy
Dubielecka, Patrycja Oct 17, 2019 Signaling at the Crossroads: From Inflammaging to Cancer
Duckett, Colin Apr 24, 2001 Role of IAP Proteins in the Control of Cell Survival
Du, Hong-Yan Oct 28, 2005 Work-in-Progress
Feb 9, 2007 TERT Haploinsufficiency and Telomere Length in Individuals with 5p- Syndrome
Jan 18, 2008 The Significance of Telomere Length Measurement in the Diagnosis of Dyskeratosis Congenita
Duncavage, Eric Feb 28, 2014 Detection of Subclonal Population in MDS
Oct 31, 2014 Sequencing Based Detection of Low Frequency Variants in MDS
Dustin, Mike Jun 4, 1999 Visualizing Molecular Events in the Immune Response: Building an Immunological Synapse
Du, Xiaoping Sep 2, 2021 Novel Mechanisms of Integrin Outside-In Signaling and the Concept of Treating Thrombosis and Inflammation Without Causing Bleeding
Elefanty, Andrew Aug 30, 2018 Dissection of Human Haematopoiesis From Pluripotent Stem Cells
Elf, Shannon Nov 17, 2022 Type 1 and Type 2 Calreticulin Mutations Activate Discrete Unfolded Protein Response Pathways to Drive Myeloproliferative Neoplasms
Ellenberger, Tom Feb 8, 2008 Chemical Biology of DNA Repair
Ellisen, Leif Mar 24, 2000 Acute Leukemia, Telomeres and DNA Damage Responses
Ellis, Matthew Oct 4, 2013 The Genomics and Proteomics of Breast Cancer
Engle, Elizabeth May 3, 2013 Genetic Complexity and Clonal Evolution in Myeloproliferative Neoplasms
May 23, 2014 Genetic Complexity and Disease Evolution in Myeloproliferative Neoplasms
Feb 27, 2015 Intersection of Dysregulated Cytokines and Signaling in Myeloproliferative Neoplasms
Epple, Holly May 5, 2006 Work-in-Progress
Jan 19, 2007 From the Skeleton to the Cytoskeleton: Mechanisms of Osteoclast Function
Fager, Ammon Jan 11, 2016 Human Platelets Express Endothelial Protein C Receptor Which Contributes to the Binding and Activity of rFVIIa
Fehniger, Todd Nov 1, 2013 Molecular Regulation of NK Cell Development and Function
Feng, Yunfeng May 13, 2005 Work-in-Progress
Oct 13, 2006 RNAi Oriented Loss of Function Research on α-Actinin
Feb 29, 2008 Regulation of Cell Migration by α-actinin
Feys, Hendrik May 16, 2008 Understanding ADAMTS13 When Under (Shear) Stress
Field, Joshua Apr 4, 2014 The Potential Role of Invariant NKT Cells in Sickle Cell Disease
Fields, Melanie May 8, 2015 MR Measurements of Cerebral Blood Flow and Oxygen Extraction Fraction in Pediatric Sickle Cell Disease
Apr 21, 2016 Functional Connectivity in Sickle Cell Disease
Mar 30, 2017 Cerebral Oxygen Metabolism and Vasoreactivity in Sickle Cell Disease
Fisher, Daniel Jan 20, 2012 Mass Cytometry Study of Human Myeloproliferative Neoplasia
Oct 26, 2012 Genomic Study of Myeloproliferative Neoplasia
Feb 14, 2014 Signaling in Myeloproliferative Neoplasms Studied by Single Cell Mass Cytometry
Sep 26, 2014 Mass Cytometry Study Identifies NFκB Signaling as a Potential Disease Driver in Myeloproliferative Neoplasms
Sep 10, 2015 NFkB Hyperactivation in Myeloproliferative Neoplasms
Apr 13, 2017 Cytokines and Intracellular Signaling Abnormalities in Myeloproliterative Neoplasms
Jan 25, 2018 Utilizing Mass Cytometry and Mouse Models to Understand Myeloproliferative Neoplasms
Jan 24, 2019 Interacting Roles of Hyperactive Signaling and Cytokine Overproduction in Myeloproliferative Neoplasms
Jan 30, 2020 NFκB Hyperactivation in Myeloproliferative Neoplasms: Insights From Human Patients and Mouse Models
Sep 17, 2020 NF kappa B Hyperactivation in Myeloproliferative Neoplasms
Sep 23, 2021 JAK2 and NF Kappa B Hyperactivation in Mouse Hematopoiesis and Myeloproliferative Neoplasms
Flaumenhaft, Robert Mar 9, 2020 Test Tube to Trial: Protein Disulfide Isomerase as an Antithrombotic Target
Fleischman, Angela Sep 28, 2017 Inflammation as a Driver of Clonal Expansion in Myeloproliferative Neoplasm
Fok, Wilson Nov 14, 2014 Telomere Dysfunction in Stem Cell Proliferation and Differentiation
Oct 15, 2015 Telomere Dysfunction in Stem Cell Proliferation and Differentiation
Sep 22, 2016 p53 Stabilization Following Progressive Telomere Shortening Differentially Regulates Human Hematopoietic Specification
Oct 5, 2017 Understanding How Telomere Dysfunction and RNA Processing Defects Lead to Human Disease
Oct 25, 2018 Inhibition of Polyadenylation Activity by Silencing of PAPD5 Restores Telomerase and Rescues Hematopoietic Failure in Dyskeratosis Congenita
Fowles, Jared Apr 27, 2017 Genomic Dissection of Age-Related Differences in Polycythemia Vera
Feb 1, 2018 Genomic Dissection of Age-Related Differences in Polycythemia Vera
Feb 21, 2019 Investigating the Genomic and Inflammatory Profiles of Young and Old Polycythemia Patients
Nov 5, 2020 Dysregulated Inflammation in Myeloproliferative Neoplasms and Disease Progression
Frazier, Bill Oct 13, 1995 Thrombospondin as a Regulator of Endothelial Phenotype
Mar 22, 2002 Integrin Associated Protein (CD47): a Receptor With Multiple Roles in Vascular Disease
French, Anthony Apr 3, 2015 Regulation of NK Cell Proliferation
Friedman, Jeffrey Oct 24, 1997 25th Carl Moore Lecture: Leptin, Leptin Receptors and the Control of Body Weight
Fuh, Katherine Mar 31, 2016 Functional Genomics of Ovarian Cancer Metastasis
Fujiki, Yukio Mar 5, 2010 Peroxisome Biogenesis and Its Dysfunctions in Humans
Gadue, Paul J. Apr 5, 2018 Megakaryocyte Development From Stem Cell Sources
Gailani, Dave Apr 7, 1995 The Role of Factor XI in a Revised Model of Blood Coagulation
Mar 26, 2010 Factor XI and the Intrinsic Pathway in Normal and Pathologic Coagulation
Ganem, Donald Nov 21, 2008 36th Carl Moore Lecture: Small Noncoding RNAs and the Biology of Kaposi's Sarcoma-Associated Herpesvirus
Ganz, Tomas Jan 23, 2015 Systemic Iron Homeostasis and Its Disorders
Gao, Weiqiang Oct 21, 2005 Work-in-Progress
Sep 15, 2006 A C-terminal Exosite of von Willebrand Factor Domain A2 Interacts with ADAMTS13 Spacer Domain to Accelerate Substrate Cleavage
Oct 26, 2007 Contacts Between Several ADAMTS13 Structural Domains and Von Willebrand Factor Domain A2 Contribute to Substrate Cleavage
Apr 10, 2009 Fluorescent VWF Substrates for ADAMTS13
May 21, 2010 Functional Differences of the Non-Catalytic Domains in Human ADAMTS13 and ADAMTS5 in Substrate Cleavage
Ge, Jingping May 4, 2007 Study of the Function of Dyskerin in a Liver Specific Knock-out Mouse Model
Apr 11, 2008 Is Dyskerin Essential for Cell Survival and Proliferation?
Jan 30, 2009 Microarray Analysis of snoRNA Expression in Dyskerin Knockout Mice
Feb 5, 2010 The Consequences of Dyskerin Ablation in Mouse Liver
Germain, David May 23, 2014 DNMT3A Mutations in AML
Geuze, Hans Dec 16, 1993 New Observations on the Class II Compartment in B Lymphoblasts
Gilligan, Diana Mar 7, 2000 Knockout of Beta-Adducin Causes Spherocytosis in Mice
Gilliland, Gary Oct 14, 1994 Early Mutations in Leukemia
Ginsburg, David Feb 21, 2003 Disorders of Hemostasis Due to Genes Outside of the Coagulation System
Jan 7, 2021 FV/FVIII and Cargo Receptors in the ER: From Bedside to Bench
Girard, Tom Jan 7, 2011 The Ups and Downs of Protein Z and the Z-dependent Protease Inhibitor
Feb 3, 2012 Tissue Factor Pathway Inhibitor - βefore and αfter
Nov 16, 2012 Protein Z, Protein Z-Dependent Protease Inhibitor (SerpinA10) and the Acute Phase Response
Oct 25, 2013 Tissue Factor Pathway Inhibitor Structures, Functions and Physiology
Sep 5, 2014 Impact of Coagulation Regulators in Mouse Models of Various Diseases
Dec 10, 2015 Evaluating Blockade of the Protein Z-Dependent Protease Inhibitor Pathway as a Potential Treatment for Hemophilia
Jan 12, 2017 The Roles of Tissue Factor Pathway Inhibitor in Health and Disease
Feb 15, 2018 A Balance Between Pro- and Anti-Coagulant Factors to Abate Bleeding and Avoid Thrombosis
May 2, 2019 The TFPIαβ (γKO) Mouse Is a Better Model for Studying Human TF-Related Diseases
Giri, Tusar Mar 10, 2006 Work-in-Progress
Gitlin, Jonathan May 9, 1997 Aceruloplasminemia
Oct 6, 2000 The Copper Chaperones
May 2, 2008 Copper Homeostasis in Early Development
Glimcher, Laurie Oct 31, 2019 Stanley J. Korsmeyer Memorial Lecture: ER Stress: Reprogramming the Tumor Microenvironment
Goate, Alison Jan 13, 2006 A Novel Risk Factor for Alzheimer's Disease on Chromosome 10
Goldberg, Dan Apr 24, 1998 The Pathway of Hemoglobin Degradation in the Malaria Parasite P. falciparum
Jan 10, 2003 Falciparum Malaria: a Hematological Infectious Disease
Apr 4, 2008 Targeting Intraerythrocytic Malaria Parasites for Chemical Destruction
Dec 14, 2012 Trial by Fire and Famine: How the Malaria Parasite Survives in Its Host Erythrocyte
Goldsmith, Mark Jun 9, 1994 Structure/Function Relationships Within the IL-2 Receptor Complex
Gopalan, Priya Oct 10, 2008 Regulation of Hematopoietic Stem Cells by the Bone Marrow Niche
Govero, Jennifer Apr 18, 2008 Characterization of the GGA Null Mice
Nov 14, 2008 Characterization of the GGA Null Mice
Mar 19, 2010 All GGAs Are Not Created Equal
Feb 4, 2011 Strain Dependent Lethality of GGA2 Null Mice: Embryonic vs Neonatal
Grainger, Stephanie Apr 20, 2021 From Fish to Dish and Back Again: Deciphering Wnt/Fzd Cues in Hematopoietic Stem Cell Development
Graubert, Tim Mar 14, 2003 Modeling T(8;21) Associated Acute Myelogenous Leukemia in Mice
May 23, 2008 Genetic Basis of Susceptibility to Therapy-Related Leukemia
Greenberg, Zev Feb 28, 2019 Regulation of Early B Cell Development by the Tetraspanin CD53
Jan 30, 2020 Loss of CD53 Impairs B Cell Migration
Apr 21, 2022 The Tetraspanin CD53 Protects Hematopoietic Stem Cells Following Cellular Stress Through Induction of DREAM Complex-Mediated Quiescence
Green, Eric Nov 11, 2005 33rd Carl Moore Lecture: Comparative Genomics: Using Evolution to Decode the Human Genome
Grierson, Patrick May 9, 2019 Overcoming the MK2/ Hsp27 Axis to Potentiate the Effect of Chemotherapy in Pancreatic Ductal Adenocarcinoma (PDAC)
Jan 9, 2020 The MK2/Hsp27 Axis Determines Sensitivity to Chemotherapy in Pancreatic Ductal Adenocarcinoma
Gu, Baiwei Oct 27, 2006 Molecular Mechanism of Mouse Dyskerin Mutation in Telomere Maintenance and Ribosomal RNA Processing
Oct 12, 2007 Dyskerin, Telomerase and DNA Damage
Sep 19, 2008 Is Dyskerin Crucial for Telomere Maintenance, DNA Damage Response and Ageing?
Sep 18, 2009 DNA Damage Accumulation, Accelerated Hematopoietic Stem Cell Aging, and Partial Reversal by Antioxidant Treatment in a Mouse Model of Dyskeratosis Congenita
Gu, Minxiang Jun 12, 1998 Characterization of a Novel Protein Tyrosine Phosphatase - PTPMEG
Gupta, Garima Mar 1, 2013 Non-catalytic Interaction Between VWF and ADAMTS-13
Hahn, William Apr 21, 2000 Telomerase Immortality in Cancer
Hajjar, Kathy Apr 8, 1994 Annexin II: a New Thromboregulatory Protein?
Halldorsdottir, Anna Margret Sep 30, 2005 Work-in-Progress
Hambleton, Julie Apr 5, 1996 Activation of MAP Kinase Signaling Pathways in Monocyte/Macrophage Cells
Hancock, John Mar 3, 1995 Ras Proteins: Membrane Targeting and Biochemical Function
Sep 17, 1999 Caveolae, Cholesterol and Trafficking: New Insights Into Biological Differences Between the Ras Proteins
Harris, David May 23, 1997 Prion Diseases: a Cell Biological Perspective
Feb 22, 2002 Molecular Mechanisms Underlying Familial Prion Diseases
He, Fan Feb 11, 2021 The Characteristics of Platelets in Essential Thrombocythemia
Feb 10, 2022 The Metabolic Dysregulation of Platelets in MPN Disease
Heinecke, Jay Jan 11, 2002 Regulation of Matrix Metalloproteinase Activation and Plaque Rupture by Myeloperoxidase
He, Jun Feb 18, 2005 Work-in-Progress
May 19, 2006 Work-in-Progress
Heldermon, Coy Sep 5, 2008 The Effect of Bone Marrow Transplant and Intracranial Gene Therapy in Mucopolysaccharidosis IIIB Mice
He, Li Apr 29, 2005 Work-in-Progress
Herzog, Brett Oct 24, 2019 Reactive Fibrosis in Lung Cancer: Impact on Immunity and Progression
Apr 15, 2021 Restoring Immune-Mediated Tumor Control in the Fibrotic NSCLC Microenvironment
Heslop, Helen Apr 21, 1995 Use of Virus-Specific Cytotoxic T Lymphocytes to Control Epstein-Barr Virus-Related Lymphoproliferation
High, Katherine Apr 12, 1996 Gene Therapy for Hemophilia
Jan 25, 2012 Biologic Therapeutics/Hematology Joint Seminar: in Vivo Gene Transfer for Genetic Disease: Progress and Challenges
Hiken, Jeff Mar 16, 2007 Proteomic Analysis of PNH RBCs
Feb 15, 2008 Label-free Quantitative Proteomic Analysis of Normal and PNH RBC Membranes
Oct 24, 2008 Quantitative Differences Between Expression Profiles of RBC Proteomes
Hirbe, Angela May 9, 2014 Defining the Molecular Events Underlying Malignant Transformation in NF1-related MPNSTs Through Whole Genome Sequencing
Mar 13, 2015 Whole Exome Sequencing Reveals the Temporal Sequence of Genetic Changes During Malignant Transformation and Metastasis in a Single Patient With NF1-Associated Plexiform Neurofibroma
Hobbs, Helen Nov 12, 2019 Mechanisms of Lipid Accumulation: Implications for Fatty Liver Disease
Hockemeyer, Dirk Feb 13, 2020 Elucidating the Mechanisms of Cancer Cell Immortality
Hoffmeister, Karin Feb 17, 2020 Glycans in Translational and Clinical Research
Hofmann, Sandra May 9, 1996 Palmitoyl-Protein Thioesterase and the Pathogenesis of INCL
Sep 19, 2014 Phil Majerus Symposium: Molecular Basis of Infantile Batten Disease
Hogg, Phil Apr 3, 2002 Control of Von Willebrand Factor Multimer Size by Thrombospondin-1
Horwich, Arthur Nov 16, 2007 35th Carl Moore Lecture: Protein Folding and Misfolding in the Cell
Howe, Ruth May 14, 2010 The Role of Cathepsin S and MMP-12 in MPS VII Aortic Disease
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Mann, Ken Dec 16, 1994 Modeling the Tissue Factor Pathway to Thrombosis: the Coagulation Explosion
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Oh, Steve May 20, 2011 The Missing LNK: Mechanisms of Dysregulated Signaling in Myeloproliferative Neoplasms
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Orkin, Stuart Nov 11, 1994 22nd Carl Moore Lecture: Multi-layered Regulation of Hematopoietic Development and Transcription
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Ornitz, Dave Oct 7, 1994 Regulation of FGF/FGF Receptor Activity
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Pike, Linda May 2, 2003 EGF Receptors and Lipid Rafts: Bringing Order to Chaos
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Rowley, Janet Oct 10, 2003 31st Carl Moore Lecture: New Paradigms From Leukemias
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Yu, Zheyong Feb 1, 2008 Modulation of ADAMTS13 Activity by Free Amino Acids
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Zou, Jun Nov 9, 2007 Type I Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Regulates Stress-induced Apoptosis
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