Luis F. Z. Batista, PhD
Associate Professor
Department of Medicine
Hematology Division
Department of Developmental Biology
Research Interests
- Induced pluripotent stem cells
- Telomere maintenance
Contact
- 314-362-8816 (office)
- 314-362-8826 (fax)
- lbatista@wustl.edu
- Hematology Division
Mail Stop 8125-0020-08
Washington University
660 South Euclid Avenue
St. Louis, MO 63110 - Room 8817 Clinical Sciences Research Building (office)
- Room 8816 Clinical Sciences Research Building (lab)
- Batista Lab
Research
The overarching goal of my research is to understand the importance of telomerase in human stem and progenitor cell function and regulation. I am interested in understanding how genetic instability leads to diminished pluripotent cell function over time and how it influences tissue homeostasis, human aging and cancer. My laboratory uses genome-wide methods to uncover alterations that drive cellular failure upon critical telomere dysfunction, using human pluripotent cells as a primary model. We combine in vitro biochemical and mechanistic studies with our ability to generate and differentiate pluripotent cells to better understand the importance of telomere maintenance in this process and to determine the events that lead from telomere dysfunction to human disease.
For more information, please see: www.batistalab.org
