Ramaswamy Govindan, MD

Anheuser Busch Endowed Chair in Medical Oncology, Associate Chief of Oncology

Phone: 314-747-7405
Fax: 314-362-3895
Email: rgovindan@nospam.wustl.edu

Address:
Division of Oncology
Mail Stop 8056-0029-11
Washington University
660 South Euclid Avenue
St. Louis, MO 63110

11th Floor Mid Campus Center (office)

Admin:
Kim Blasé
kblase@wustl.edu

Research Interests

Research

As a medical oncologist interested in thoracic malignancies, I have led a number of institutional and multi- center phase II and III studies in lung cancer over the past decade. Working with The McDonnell Genome Institute at the Washington University School of Medicine and with The Cancer Genome Atlas (TCGA) project (as a co-chair) sponsored by the NCI, I am actively involved in sequencing the whole genomes and exomes of several hundred patients with lung cancer. In addition, I am leading the efforts to move personalized therapies in early stage and locally advanced lung cancer. I am the Principal Investigator for the NCI funded large phase III randomized ALCHEMIST trial to study the role of erlotinib in patients with early stage EGFR mutated lung cancer. We have recently reported for the first-time mechanistic basis for acquired resistance to chemotherapy in patients with relapsed small cell lung cancer using whole exome and transcriptome sequencing. I am the Principal Investigator for the NCI funded consortium for the development of patient-derived xenograft (PDX) models to translate rapidly discoveries from bench to bedside. I have led Team Science effort through U01/U54 funded projects and the TCGA.

Profiles (publications)

WU Physician Bio

Biosketch

Education

1990: MD, University of Pondicherry, India
1986: MBBS, University of Madras, India

Post-Graduate Training

1996-1993: Fellow, Hematology/Oncology, Washington University, Department of Internal Medicine, St. Louis, MO
1993-1991: Intern and Resident, Internal Medicine, Michael Reese Hospital and Medical Center, Chicago, IL
1991-1990: Chief Resident, Jawaharlal Institute of Postgraduate Medical Education and Research, India
1990-1987: Resident, Internal Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, India

Academic Positions & Employment

present-2022: Associate Chief, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
present-2015: Director, Section of Medical Oncology, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
present-2010: Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
2015-2010: Co-Director, Section of Medical Oncology, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
2009-2003: Associate Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
2003-1998: Assistant Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
1998-1996: Attending Physician, Department of Medicine, Cook County Hospital, Chicago, IL

University & Hospital Appointments & Committees

present-2019: Member, Siteman Cancer Center External Advisory Committee
present-2019: Member, Developmental Therapeutics Core Committee
present-2018: Member, Department of Surgery Ad Hoc Committee
present-2018: Member, Washington University IRB/HRPO Advisory Committee
present-2010: Member, Protocol Adherence Review Committee, Washington University School of Medicine
present-2010: Member, Committee on Admissions, Washington University School of Medicine
present-2010: Member, Barnes-Jewish Hospital Expansion Committee
present-2008: Member, Human Research Protection Organization
present-2005: Member, Protocol Review and Monitoring Committee
2007-1999: Member, Cancer Committee, Barnes-Jewish Hospital
2004-2001: Chairman, Education Subcommittee, Barnes-Jewish Hospital Cancer Committee, Siteman Cancer Center
2004-2000: Member, Education Subcommittee, Barnes-Jewish Hospital Cancer Committee

Board Certification

2008, 1997: American Board of Internal Medicine (Medical Oncology)
1996: American Board of Internal Medicine (Hematology)
1993: American Board of Internal Medicine

Honors & Awards

2020: AACR Team Science Award
2016: Anheuser Busch Endowed Chair in Medical Oncology
2016: Alton Ochsner Award Related Smoking and Disease
2001: ASCO Clinical Research Career Development Award for research titled “A Pilot Study of Celecoxib in Patients with Barrett’s Esophagus”
1993: Alfred Pick Award for academic excellence during the Internal Medicine Residency at Michael Reese Hospital and Medical Center, Chicago, IL

International & National Committee Memberships

present-2019: Member, PierianDx Knowledgebase Expert Panel
present-2019: Member, The Cancer Genoma Atlas Lung Adenocarcimona Subgroup (TCGA LUAD) NIH/NCI
present-2018: Member, AACR Lung Cancer Research Fellowships Scientific Review Committee
present-2018: Member, ALCHEMIST Core Committee
present-2018: Member, K12 External Advisory Committee
present-2018: Member, PDX Steering Committee
present-2018: Co-Chair, SITC Lung Subcommittee
present-2018: Member, SITC Cancer Immunotherapy Guidelines (CIG) Committee
present-2014: Member, SITC/Medscape CME Project Steering Committee
present-2014: Member, ALCHEMIST Champions Team
present-2013: Member, National Comprehensive Cancer Network (NCCN) National Cancer Institute (NCI) Non-Small Cell Lung Cancer Panel
present-2012: Chair, IASLC CME Subcommittee
present-2010: Co-Chair, Lung Cancer Disease Working Group, The Cancer Genome Atlas Project
present-2009: Member, Subcommittee H, NCI
present-2009: Member, IASLC Pathology Committee
present-2008: Member, Cancer Center Review Panel, NCI
present-2008: Member, American College of Surgical Oncology (ACOSOG)
present-2008: Member, Education Committee, ASCO
present-2007: Member, NCCN Guidelines Committee, Non-Small Cell Lung Cancer
present-2002: Member, Clinical Oncology Advisory Board (COAB)
present-2001: Member, Respiratory Core Committee, Cancer and Leukemia Group B (CALGB)
present-2000: Member, Lung Committee, Hoosier Oncology Group (HOG)
present-2000: Member, Lung Steering Committee, Radiation Therapy Oncology Group (RTOG)
2019: Member, Dr. Dubinett’s CLIN2-10784 Clinical Advisory Panel
2014: Member, International Association for the Study of Lung Cancer Core Program Committee for the Treatment of Localized Disease NSCLC Track
2010: Member (ad hoc), NCI Basic, Translational and Clinical Oncology Special Emphasis Panel
2009: Member, Review Panel, American Recovery Reinvestment Act (ARRA)
2008-2007: Member (ad hoc), NCI SPORE Review Panel
2007-2005: Chair, Lung Committee (P2C-Mayo Consortium)
2007-2000: Co-Chair, Lung Committee, Hoosier Oncology Group (HOG)
2006-2004: Member, Lung Cancer Program Committee, American Society of Clinical Oncology
2005-2002: Vice-Chair, Midwest Oncology Group (MOG)
2003: Reviewer for Cancer Research UK (formerly ICRS and CRC) Phase I and II protocols
2001-1998: Member, Oncology Training Program Committee, American Society of Clinical Oncology (ASCO)
2000: Member, Quality Assurance Subcommittee, Radiation Therapy Oncology Group (RTOG)
2009: Vice Chair, Medical Oncology Committee, American College of Surgical Oncology (ACOSOG)

Editorial Responsibilities

present-2010: Cancer Pharmacology, Lippincott, Williams & Wilkins
present-2010: Oncology Advisory Editor, Oncology Times
present-2009: Clinical Care Options InPractice Oncology
present-2008: Proceedings of the Annual Targeted Therapy Meeting Summary, International Association for the Study of Lung Cancer (ISLAC)
present-1999: ASCO Training Program Committee, Reading Syllabus on ASCO website
2015: Washington Manual of Oncology, 3rd Edition, Lippincott, Williams & Wilkins Contemporary Oncology (bi-weekly newsletter/journal), Lippincott, Williams & Wilkins, Co-editor: Michael C. Perry
Thoracic Oncology Matters (quarterly), Washington University School of Medicine
2011-2008: ASCO Meeting Summaries
2011-2006: ASCO Educational Book
2009: DeVita, Hellman & Rosenberg’s “Cancer, Principles & Practice of Oncology Review” 2nd Edition, Lippincott Williams & Wilkins
2009: Lung Cancer, Monograph, Lippincott, Williams & Wilkins
2008: E-Update Series- Non-small Cell Lung Cancer, CMP Media
2007: Washington Manual of Oncology, 2nd Edition, Lippincott, Williams & Wilkins
2007: E-Update Series- Non-small Cell Lung Cancer, CMP Media
2006: Locally Advanced Non-Small-Cell Lung Cancer: Cancer Management: a Multidisciplinary Approach, CMP United Business Media/Publishers of Oncology
2005: DeVita, Hellman & Rosenberg’s “Cancer, Principles & Practice of Oncology Review”, Lippincott Williams & Wilkins
2004: Locally Advanced Non-small Cell Lung Cancer: A Practical Management Guide, a COAB publication
2002: Washington Manual of Oncology, Lippincott, Williams & Wilkins