Hematology Division
Alphabetical list (active faculty):   
Yoon-A Kang

Yoon-A Kang, PhD

Assistant Professor

Department of Medicine

Hematology Division

Research Interests

  • Hematopoietic stem cells
  • Multipotent progenitor
  • Cell fate decision
  • Lineage specification


  • 314-273-5954 (office)
  • 314-273-5991 (lab)
  • Division of Hematology
    Mail Stop 8125-0020-08
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Room 8832A, Clinical Sciences Research Building (office)
  • Room 8832, Clinical Sciences Research Building (lab)

Original Articles

  • Secretory MPP3 Reinforce Myeloid Differentiation Trajectory and Amplify Myeloid Cell Production
    Kang YA, Paik H, Zhang SY, Chen JJ, Olson OC, Mitchell CA, Collins A, Swann JW, Warr MR, Fan R, Passegue E
    J Exp Med 2023 Aug 7;220(8):e20230088
  • Aged Hematopoietic Stem Cells Are Refractory to Bloodborne Systemic Rejuvenation Interventions
    Ho TT, Dellorusso PV, Verovskaya EV, Bakker ST, Flach J, Smith LK, Ventura PB, Lansinger OM, Herault A, Zhang SY, Kang YA, Mitchell CA, Villeda SA, Passegue E
    J Exp Med 2021 Jul 5;218(7):e20210223
  • Deregulated Notch and Wnt Signaling Activates Early-Stage Myeloid Regeneration Pathways in Leukemia
    Kang YA, Pietras EM, Passegue E
    J Exp Med 2020 Mar 2;217(3):e20190787
  • Normal Hematopoiesis Is a Balancing Act of Self-Renewal and Regeneration
    Olson OC*, Kang YA*, Passegue E (*Equal contribution)
    Cold Spring Harb Perspect Med 2020 Dec 1;10(12):a035519
  • Myeloid Progenitor Cluster Formation Drives Emergency and Leukaemic Myelopoiesis
    Herault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Gottgens B, Passegue E
    Nature 2017 Apr 6;544(7648):53-58
  • Exosome Complex Orchestrates Developmental Signaling to Balance Proliferation and Differentiation During Erythropoiesis
    McIver SC, Katsumura KR, Davids E, Liu P, Kang YA, Yang D, Bresnick EH
    Elife 2016 Aug 20;5:e17877
  • Hematopoietic Signaling Mechanism Revealed From a Stem/Progenitor Cell Cistrome
    Hewitt KJ, Kim DH, Devadas P, Prathibha R, Zuo C, Sanalkumar R, Johnson KD, Kang YA, Kim JS, Dewey CN, Keles S, Bresnick EH
    Mol Cell 2015 Jul 2;59(1):62-74
  • Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions
    Pietras EM, Reynaud D, Kang YA, Carlin D, Calero-Nieto FJ, Leavitt AD, Stuart JM, Gottgens B, Passegue E
    Cell Stem Cell 2015 Jul 2;17(1):35-46
  • The Exosome Complex Establishes a Barricade to Erythroid Maturation
    McIver SC*, Kang YA*, DeVilbiss AW, O'Driscoll CA, Ouellette JN, Pope NJ, Camprecios G, Chang CJ, Yang D, Bouhassira EE, Ghaffari S, Bresnick EH (*Equal contribution)
    Blood 2014 Oct 2;124(14):2285-97
  • Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy
    Klionsky DJ and 1269 authors including Kang YA
    Autophagy 2012 Apr;8(4):445-544
  • Autophagy Driven by a Master Regulator of Hematopoiesis
    Kang YA, Sanalkumar R, O'Geen H, Linnemann AK, Chang CJ, Bouhassira EE, Farnham PJ, Keles S, Bresnick EH
    Mol Cell Biol 2012 Jan;32(1):226-39
  • Discovering Hematopoietic Mechanisms Through Genome-Wide Analysis of GATA Factor Chromatin Occupancy
    Fujiwara T, O'Geen H, Keles S, Blahnik K, Linnemann AK, Kang YA, Choi K, Farnham PJ, Bresnick EH
    Mol Cell 2009 Nov 25;36(4):667-81
  • Short Hairpin RNA-Expressing Oncolytic Adenovirus-Mediated Inhibition of IL-8: Effects on Antiangiogenesis and Tumor Growth Inhibition
    Yoo JY, Kim JH, Kim J, Huang JH, Zhang SN, Kang YA, Kim H, Yun CO
    Gene Ther 2008 May;15(9):635-51
  • Novel Cancer Antiangiotherapy Using the VEGF Promoter-Targeted Artificial Zinc-Finger Protein And Oncolytic Adenovirus
    Kang YA*, Shin HC*, Yoo JY, Kim JH, Kim JS, Yun CO (*Equal contribution)
    Mol Ther 2008 Jun;16(6):1033-40
  • Transduction of Artificial Transcriptional Regulatory Proteins Into Human Cells
    Yun CO, Shin HC, Kim TD, Yoon WH, Kang YA, Kwon HS, Kim SK, Kim JS
    Nucleic Acids Res 2008 Sep;36(16):e103