Mia C. Weiss, MD

Mia C. Weiss, MD

Assistant Professor

Address:
Division of Oncology
Mail Stop 8056-0029-11
Washington University
660 South Euclid Avenue
St. Louis, MO 63110

Room 11310, Mid Campus Center (office)

Admin:
Terrie Stald
tstald@wustl.edu

Clinical Interests
  • Bone and soft tissue sarcoma
Research Interests
  • Clinical trials in soft tissue and bone sarcoma
  • Precision medicine and genomics
  • Sarcoma in older adults
Research

As a medical oncologist my career is dedicated to the care of patients with soft tissue and bone sarcomas. I am developing clinical trials to study novel targeted therapies in this patient population and to elucidate the reasons why some patients respond to targeted therapy while others do not. In addition, given my particular interest in geriatrics, I am looking at ways to optimize care for older adults with bone and soft tissue sarcoma, and to utilize genomic sequencing to establish clinical trials specifically for this patient population for which therapeutic options can often be limited.

I serve currently as Site Principal Investigator on several clinical trials in medical oncology:

  • 201801202: A Phase IB Trial Of Neoadjuvant AMG 232 Concurrent With Preoperative Radiotherapy In Wild-Type P53 Soft Tissue Sarcoma (STS)
  • 201904129: A Randomized Study Comparing the Efficacy of the Combination of Doxorubicin and the Tumor-Targeting Human Antibody-Cytokine Fusion Protein L19TNF to Doxorubicin Alone as First-Line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma
  • 201911176: A Phase 1b/3 Global, Randomized, Double-blind, Placebo-Controlled Trial of Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma
  • 202001168: A Phase 2, Single-Arm Open-Label Study of Abemaciclib for Treatment of Advanced Bone and Soft Tissue Sarcoma Identified as having CDK Pathway Alteration
  • 202002113: A Phase II Study of Cabozantinib and Temozolomide in Patients with Unresectable or Metastatic Leiomyosarcoma and Other Soft Tissue Sarcomas
  • 202008172: NCI Protocol 10330, A Phase 2 Study of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma
  • 202010010: Envasarc: A Pivotal Trial Of Envafolimab, And Envafolimab In Combination With Ipilimumab, In Patients With Advanced Or Metastatic Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma Who Have Progressed On Prior Chemotherapy
  • 202102173: A Multicenter Phase 1, Open-Label Study of SQ3370 in Patients with Advanced Solid Tumors
  • 202103092: A Multicenter Phase 1, Open-Label Study of SQ3370 in Patients with Advanced Solid Tumors
  • 202108161: SARC041: Phase 3 Randomized Double-Blind Study of Abemaciclib versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma
  • 202112086: A dose escalation and dose expansion study of NOX66 plus doxorubicin in anthracycline-naïve, adult patients with soft tissue sarcoma – CEP-2

Biosketch

Education

  • 2014-2010: MD, University of Tel Aviv, Sackler School of Medicine, Tel Aviv, Israel
  • 2010-2006: BA, Smith College, Northampton, MA

Post-Graduate Training

  • 2020-2019: Chief Fellow, Division of Hematology, Oncology and Cell Therapy, Rush University Medical Center, Chicago, IL
  • 2019-2017: Fellow, Division of Hematology, Oncology and Cell Therapy, Rush University Medical Center, Chicago, IL
  • 2017-2014: Resident, Department of Internal Medicine, University of Chicago, Chicago, IL

Academic Positions & Employment

  • present-2020: Assistant Professor of Medicine, Washington University Medical School, St. Louis, MO

Board Certification

  • 2020: American Board of Internal Medicine – Medical Oncology
  • 2017: American Board of Internal Medicine

Professional Societies & Organizations

  • 2020: Connective Tissue Oncology Society
  • 2017: American Society of Clinical Oncology