Andrew L. Young

Andrew L. Young, MD, PhD

Third-year Fellow

Began fellowship in 2020


2003-2007 BA, Washington University, St. Louis, MO
2010-2018 MD/PhD, Washington University, St. Louis, MO
Post-graduate Training
2018-2020 Residency, Internal Medicine, Barnes-Jewish Hospital/Washington University, St. Louis, MO
Honors & Awards
Spencer T. and Ann W. Olin Medical Science Fellow
2015 Best Oral Presentation, Molecular Genetics and Genomics Retreat
2017 Abstract Achievement Award, American Society of Hematology Annual Meeting
2019 Intern of the Month (March), Barnes Jewish Hospital
2019 Intern of the Year, John Cochran Veterans Hospital

Peer-reviewed Journal Articles

  • KDM6B Protects T-ALL Cells From NOTCH1-Induced Oncogenic Stress
    Issa N, Bjeije H, Wilson ER, Krishnan A, Dunuwille WMB, Parsons TM, Zhang CR, Han W, Young AL, Ren Z, Ge K, Wang ES, Weng AP, Cashen A, Spencer DH, Challen GA
    Leukemia 2023 Feb 17; [ahead of print]
  • Effect of Clonal Hematopoiesis on Cardiovascular Disease in People Living With HIV
    Wiley B, Parsons TM, Burkart S, Young AL, Erlandson KM, Tassiopoulos KK, Wu K, Gurnett C, Presti RM, Bolton KL, Challen GA
    Exp Hematol 2022 Oct;114:18-21
  • Cancer Therapy Shapes the Fitness Landscape of Clonal Hematopoiesis
    Bolton KL, Ptashkin RN, Gao T, Braunstein L, Devlin SM, Kelly D, Patel M, Berthon A, Syed A, Yabe M, Coombs CC, Caltabellotta NM, Walsh M, Offit K, Stadler Z, Mandelker D, Schulman J, Patel A, Philip J, Bernard E, Gundem G, Ossa JEA, Levine M, Martinez JSM, Farnoud N, Glodzik D, Li S, Robson ME, Lee C, Pharoah PDP, Stopsack KH, Spitzer B, Mantha S, Fagin J, Boucai L, Gibson CJ, Ebert BL, Young AL, Druley T, Takahashi K, Gillis N, Ball M, Padron E, Hyman DM, Baselga J, Norton L, Gardos S, Klimek VM, Scher H, Bajorin D, Paraiso E, Benayed R, Arcila ME, Ladanyi M, Solit DB, Berger MF, Tallman M, Garcia-Closas M, Chatterjee N, Diaz LA Jr, Levine RL, Morton LM, Zehir A, Papaemmanuil E
    Nat Genet 2020 Nov;52(11):1219-1226
  • The Evolutionary Dynamics and Fitness Landscape of Clonal Hematopoiesis
    Watson CJ, Papula AL, Poon GYP, Wong WH, Young AL, Druley TE, Fisher DS, Blundell JR
    Science 2020 Mar 27;367(6485):1449-1454
  • The Zebrafish Xenograft Platform-A Novel Tool for Modeling KSHV-Associated Diseases
    Pringle ES, Wertman J, Melong N, Coombs AJ, Young AL, O'Leary D, Veinotte C, Robinson CA, Ha MN, Dellaire G, Druley TE, McCormick C, Berman JN
    Viruses 2019 Dec 20;12(1)
  • Clonal Hematopoiesis and Risk of Acute Myeloid Leukemia
    Young AL, Tong RS, Birmann BM, Druley TE
    Haematologica 2019 Dec;104(12):2410-2417
  • Rare Event Detection Using Error-Corrected DNA and RNA Sequencing
    Wong WH, Tong RS, Young AL, Druley TE
    J Vis Exp 2018 Aug 3;(138)
  • Dnmt3a Regulates T-Cell Development and Suppresses T-ALL Transformation
    Kramer AC, Kothari A, Wilson WC, Celik H, Nikitas J, Mallaney C, Ostrander EL, Eultgen E, Martens A, Valentine MC, Young AL, Druley TE, Figueroa ME, Zhang B, Challen GA
    Leukemia 2017 Nov;31(11):2479-2490
  • Rapid Detection of Donor Cell Free DNA in Lung Transplant Recipients With Rejections Using Donor-Recipient HLA Mismatch
    Zou J, Duffy B, Slade M, Young AL, Steward N, Hachem R, Mohanakumar T
    Hum Immunol 2017 Apr;78(4):342-349
  • Clonal Haematopoiesis Harbouring AML-Associated Mutations Is Ubiquitous in Healthy Adults
    Young AL, Challen GA, Birmann BM, Druley TE
    Nat Commun 2016 Aug 22;7:12484
  • Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy
    Torgerson DG, Giri T, Druley TE, Zheng J, Huntsman S, Seibold MA, Young AL, Schweiger T, Yin-Declue H, Sajol GD, Schechtman KB, Hernandez RD, Randolph AG, Bacharier LB, Castro M
    PLoS One 2015 Nov 20;10(11):e0142649
  • Quantifying Ultra-Rare Pre-Leukemic Clones Via Targeted Error-Corrected Sequencing
    Young AL, Wong TN, Hughes AE, Heath SE, Ley TJ, Link DC, Druley TE
    Leukemia 2015 Jul;29(7):1608-11
  • Role of TP53 Mutations in the Origin and Evolution of Therapy-Related Acute Myeloid Leukaemia
    Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, Westervelt P, DiPersio JF, Walter MJ, Graubert TA, Ley TJ, Druley T, Link DC, Wilson RK
    Nature 2015 Feb 26;518(7540):552-555
  • Population-Based Rare Variant Detection Via Pooled Exome or Custom Hybridization Capture With or Without Individual Indexing
    Ramos E, Levinson BT, Chasnoff S, Hughes A, Young AL, Thornton K, Li A, Vallania FL, Province M, Druley TE
    BMC Genomics 2012 Dec 6;13:683