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Genetically Modified T-Cells Induce Responses in Patients with Aggressive Sarcomas

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Brian Van Tine, MD, PhD, Professor of Medicine in the Division of Oncology is the senior author of a clinical trial of CAR-T (chimeric antigen receptor T-cells) cells director against MAGE-A4. 36 of patients with aggressive sarcomas had a tumor response including some patients who entered complete remissions.