Matthew J. Christopher, MD, PhD
Assistant Professor
- Phone: 314-273-0286
- Fax: 314-362-1953
- Email: christopherm@nospam.wustl.edu
Address:
Division of Oncology
Mail Stop 8007-0057-07
Washington University
660 South Euclid Avenue
St. Louis, MO 63110
Room 741, Southwest Tower (office)
Room 740, Southwest Tower (lab)
Admin:
Shannon Dobbs
dobbss@wustl.edu
- Hematopoietic malignancies
- Hematopoietic stem cell transplantation
- Acute myeloid leukemia
- Genomics
- WT1
Currently, I split my time between directing a basic science research lab and taking care of patients with hematologic malignancies, both on our inpatient bone marrow transplant service and in an outpatient clinic. In the lab we use a variety of approaches including genomic analysis of primary samples, mouse modeling including patient-derived xenografts, and in vitro culture of primary samples to study the molecular pathogenesis of blood cancers, with a special focus on understanding the mechanisms of leukemia relapse after stem cell transplantation. Current research projects include studying the role of MHC class II downregulation in AML that relapses after transplant, studying the role of wild type and mutant WT1 in AML, and developing new cellular therapies such as CAR-T cells for AML.
Biosketch
Education
- 2010-2000: MD/PhD, Washington University School of Medicine, St. Louis, MO
- 1999-1997: Premedical Curriculum, Washington University, St. Louis, MO
- 1993-1988: BA in History/French, Saint Louis University, St. Louis, MO
Post-Graduate Training
- 2016-2013: Hematology/Oncology Fellow, Washington University School of Medicine, St. Louis, MO
- 2012-2010: Internal Medicine Resident, Barnes-Jewish Hospital, St. Louis, MO
Academic Positions & Employment
- present-2018: Assistant Professor, Department of Medicine, Washington University School of Medicine, St. Louis, MO
- 2018-2016: Instructor, Department of Medicine, Washington University School of Medicine, St. Louis, MO
- 2000-1998: Laboratory Technician, Washington University School of Medicine, St. Louis, MO
- 1997-1993: English Teacher, Havlickovo Gymnazium, Havlickuv Brod, Czech Republic
Board Certification
- 2016: American Board of Internal Medicine – Oncology Subspecialty Board
- 2013: American Board of Internal Medicine
Honors & Awards
- 2017, 2005: First Prize Plenary Abstract Competition, Hematopoietic Development and Malignancy Program Annual Retreat
- 2016-2010: Physician-Scientist Training Program, Washington University
- 2008-2005: ASH Annual Meeting Travel Award, American Society of Hematology
- 2004-2003: Howard Hughes Medical Student Research Fellowship
Professional Societies & Organizations
- present-2017: Member, American Society of Bone Marrow Transplantation
- present-2017: Member, American Society of Hematology