Peter G. Ruminski, MS

Peter G. Ruminski, MS

Instructor

Address:
Division of Oncology
Mail Stop 8007-0002-02
Washington University
660 South Euclid Avenue
St. Louis, MO 63110

Room 2607, Cancer Research Building (lab)

Research Interests
  • Developing new and novel drugs for the treatment of diseases with unmet medical needs, especially in the area of oncology
Research

I am an accomplished pharmaceutical scientist with over 42 years of research experience and project leadership, and have extensive experience in the development of drug candidates and advancing them into human clinical trials. I have a strong synthetic medicinal chemistry and molecular biology background and an exceptional ability to organize and lead cross-disciplinary teams within a fast-paced, results-oriented matrix environment. While working at Pfizer, I provided leadership and expertise in the areas of medicinal chemistry, drug design, building of IP small molecule portfolios, patent writing and evaluation, and pharmacology, with a particular emphasis on the biology/chemistry interface, cell signaling pathways, RGD integrin antagonists, protein kinases, transcription factors, and epigenetic modifications. This has led to personal contributions to the discovery and development of multiple proprietary clinical drug candidates and significant fundamental scientific advancements in the areas of oncology, hematopoietic stem cell biology, autoimmune and inflammatory diseases, ophthalmology, angiogenesis, fibrosis, osteoporosis and anemia. This expertise positions me to effectively organize and guide the translation of basic research discoveries and developed leads into viable drug candidates for the diseases we will target. I am a recognized expert in RGD peptidomimetics as integrin antagonists and have been an invited speaker at numerous conferences and symposia. Additionally, my extensive experience in initiating and successfully managing internal and external (academic, contract, etc.) collaborations is critical to our efforts to sustain synergies and partnerships with international academic, governmental, industrial and organizational entities.

Biosketch

Education

  • 1992: MS in Molecular Biology, Washington University, St. Louis, MO
  • 1975: BA in Chemistry and Education, Saint Louis University, St. Louis, MO

Academic Positions & Employment

  • present-2017: Instructor in Medicine, Division of Oncology, Washington University, St. Louis, MO
  • 2017-2010: Executive Director, Center for World Health & Medicine, Saint Louis University, St. Louis, MO
  • 2010-2002: Associate Research Fellow, Department of Medicinal Chemistry / Inflammation, Anemia, and Immunology, Pfizer Inc., Global Research and Development, St. Louis, MO
  • 2002-1999: Associate Research Fellow, Department of Medicinal Chemistry / Inflammation and Oncology, Pharmacia Corporation, Global Research and Development, St. Louis, MO
  • 1999-1991: Senior Research Scientist, Department of Medicinal Chemistry / Oncology, Ophthalmology, Inflammation and Metabolic Disease, G.D. Searle Global Research and Development, St. Louis MO
  • 1991-1979: Research Scientist / Senior Research Specialist, Monsanto Corporate Research, St. Louis, MO
  • 1977-1975: Research Associate, St. Louis University School of Medicine, St. Louis, MO

Honors & Awards

  • 2015: Saint Louis University Research Innovation Award
  • 2010: Health Care Hero Award, Saint Louis Business Journal
  • 2009-1997: Numerous internal (Monsanto, Searle, Pharmacia, Pfizer) awards for significant scientific achievements in the discovery, development and delivery of drug candidates for human clinical trials in various therapeutic disease areas
  • 2006: Lifetime Technical Achievement Award in Medicinal Organic Chemistry, American Chemical Society
  • 2000: Session Chair, Integrin Antagonists as Pharmaceutical Therapeutics, ACS National Meeting, Division of Medicinal Chemistry, Washington, DC

Professional Societies & Organizations

  • American Chemical Society
  • American Chemical Society – Division of Medicinal Chemistry
  • American Association for the Advancement of Science
  • Alpha Sigma Nu Honor Society