William C. Eades Jr.

William C. Eades Jr.

Associate Professor

Address:
Division of Oncology
Mail Stop 8007-0057-07
Washington University
660 South Euclid Avenue
St. Louis, MO 63110

702A Southwest Tower (office)
702-704 Southwest Tower (lab)

Research Interests
  • Isolation techniques for background autofluorescence
  • Extreme wavelength laser integration to flow cytometry (<350nm and >750nm)
  • Carbon based semiconductor dye conjugate development
Research

Continued management and resource management development of the Siteman Cancer Center High Speed Sorter Core Laboratory, established in 2001.

Current projects include:

  • Adaptation of FACScan flow cytometers to three laser, 8 color capable analyzers, replacing analog processing paths with fully digital, and software with post acquisition compensation control.
  • Further development of model organism parallel cell sorters in order to enhance analysis sensitivity and sorting purity. This sorter for strictly model organisms has four sort modules within a single chassis.
  • Continued GMP process cell sorting and protocol development from an existing Biological Safety Cabinet parallel sorter having been used for human cell sorting since 2007.
  • Data management for files acquired on analyzers or sorters that involves a centralized private server that stores data acquired since 2001.
Profiles (publications)

Biosketch

Education

  • 1982-1978: Electrical Engineering, University of Missouri, Rolla, MO
  • 1979: Engineering Design Drafting, Saint Louis Technical College, St. Louis, MO
  • 1974: Private Pilot Certificate, Mark Aero School of Aeronautics, St. Louis, MO

Academic Positions & Employment

  • present-2016: Director, Department of Medicine Flow Cytometry Core Lab, Washington University School of Medicine, St. Louis, MO
  • present-2015: Associate Professor, Department of Medicine, Washington University School of Medicine, St. Louis, MO
  • present-2013: Director, Siteman Flow Cytometry Core Lab, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
  • 2013-2010: Co-Director, Siteman Flow Cytometry Core Lab, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
  • 2015-2007: Assistant Professor, Department of Medicine, Washington University School of Medicine, St. Louis, MO
  • 2007-2005: Research Scientist, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
  • 2010-2003: Lab Manager, High Speed Sorter Core Lab, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
  • 2005-2001: Research Associate, Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO
  • 2001-1997: Research/Clinical Field Service Engineer, Flow Cytometry, Becton Dickinson Corporation, San Jose, CA
  • 1997-1993: Field Service Engineer, Flow Cytometry, Coulter Electronics Corporation, Miami, FL

University Appointments & Committees

  • present-2006: Institutional Biological & Chemical Safety Committee consultant for cell sorting
  • 2007-2001: EHS laser safety ombudsman
  • 2006-2003: Represented Siteman Cancer Center core labs and BMT/SCB section during three phases of design and construction of Southwest Tower

Honors & Awards

  • 2006: Missouri Whitewater Association Life Member
  • 1999: Distinguished Service Award, Becton Dickinson Immunocytometry Systems
  • 1997, 1995: Service Star Awards for Excellence, Coulter Electronics Corporation
  • 1996: U.S. Field Service Engineer of the Year Award, Coulter Electronics Corporation
  • 1990: Teammate of Distinction Award, Avionics, McDonnell Douglas Corporation
  • 1986: U.S. Jaycees District Director appointment

External Advisory Boards

  • present-2018: Bennubio – acoustic focusing cytometry development advisory
  • present-2018: MiFtek Corporation – single spectral view cytometry development advisory
  • present-2017, 2014-2012: Thermo Fisher Scientific – flow cytometry key opinion leader advisory
  • present-2016: Bio-Rad Laboratories – flow cytometry key opinion leader advisory
  • present-2016: Propel Labs, Inc. – flow cytometry instrumentation advisory/beta evaluation
  • present-2012: Leinco Technologies – flow cytometry reagent/consumables consultant
  • 2017: University of Nebraska, Omaha – flow core external advisory
  • 2017-2010: Kansas University Medical School – flow core external advisory
  • 2016-2009: Beckman Coulter Corporation – cell sorter, analyzer, and software design
  • 2016-2013: Treestar, Inc. – FlowJo scientific advisory board member
  • 2016-2011: Cytek Development – flow cytometer acquisition software design
  • 2016-2006: Sony Biotechnology, Inc. – cell sorter design/optical integration
  • 2013: University of Texas, San Antonio – Cancer Center Support Grant advisory
  • 2012, 2005: Saint Louis University Medical School – cell sorting consultation
  • 2010: New York University Medical School – cell sorter expansion consultant

Professional Societies & Organizations

  • present-2005, 2001-1998: International Society of Analytical Cytology
  • 2016-2008: Great Plains Analytical Cytometry Association
    • 2011: President
  • 2015-2009: Great Lakes International Imaging and Flow Cytometry Association
  • 2012-2011: Steering Committee member
  • 2008-2006: ISAC Biosafety Issues Surveillance Committee
  • 1991-1988: Society of Automotive Engineers – Aerospace Council