Ramaswamy Govindan, MD

Ramaswamy Govindan, MD

Anheuser Busch Endowed Chair in Medical Oncology, Associate Chief of Oncology

Address:
Division of Oncology
Mail Stop 8056-0029-11
Washington University
660 South Euclid Avenue
St. Louis, MO 63110

11th Floor Mid Campus Center (office)

Admin:
Kim Blasé
kblase@wustl.edu

Research Interests
  • Lung cancer
  • Cancer genomics
Research

As a medical oncologist interested in thoracic malignancies, I have led a number of institutional and multi- center phase II and III studies in lung cancer over the past decade. Working with The McDonnell Genome Institute at the Washington University School of Medicine and with The Cancer Genome Atlas (TCGA) project (as a co-chair) sponsored by the NCI, I am actively involved in sequencing the whole genomes and exomes of several hundred patients with lung cancer. In addition, I am leading the efforts to move personalized therapies in early stage and locally advanced lung cancer. I am the Principal Investigator for the NCI funded large phase III randomized ALCHEMIST trial to study the role of erlotinib in patients with early stage EGFR mutated lung cancer. We have recently reported for the first-time mechanistic basis for acquired resistance to chemotherapy in patients with relapsed small cell lung cancer using whole exome and transcriptome sequencing. I am the Principal Investigator for the NCI funded consortium for the development of patient-derived xenograft (PDX) models to translate rapidly discoveries from bench to bedside. I have led Team Science effort through U01/U54 funded projects and the TCGA.

Profiles (publications)
WU Physician Bio

Biosketch

Education

  • 1990: MD, University of Pondicherry, India
  • 1986: MBBS, University of Madras, India

Post-Graduate Training

  • 1996-1993: Fellow, Hematology/Oncology, Washington University, Department of Internal Medicine, St. Louis, MO
  • 1993-1991: Intern and Resident, Internal Medicine, Michael Reese Hospital and Medical Center, Chicago, IL
  • 1991-1990: Chief Resident, Jawaharlal Institute of Postgraduate Medical Education and Research, India
  • 1990-1987: Resident, Internal Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, India

Academic Positions & Employment

  • present-2022: Associate Chief, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
  • present-2015: Director, Section of Medical Oncology, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
  • present-2010: Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
  • 2015-2010: Co-Director, Section of Medical Oncology, Division of Oncology, Department of Medicine, Washington University, St Louis, MO
  • 2009-2003: Associate Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
  • 2003-1998: Assistant Professor, Department of Medicine, Washington University Medical School, St. Louis, MO
  • 1998-1996: Attending Physician, Department of Medicine, Cook County Hospital, Chicago, IL

University & Hospital Appointments & Committees

  • present-2019: Member, Siteman Cancer Center External Advisory Committee
  • present-2019: Member, Developmental Therapeutics Core Committee
  • present-2018: Member, Department of Surgery Ad Hoc Committee
  • present-2018: Member, Washington University IRB/HRPO Advisory Committee
  • present-2010: Member, Protocol Adherence Review Committee, Washington University School of Medicine
  • present-2010: Member, Committee on Admissions, Washington University School of Medicine
  • present-2010: Member, Barnes-Jewish Hospital Expansion Committee
  • present-2008: Member, Human Research Protection Organization
  • present-2005: Member, Protocol Review and Monitoring Committee
  • 2007-1999: Member, Cancer Committee, Barnes-Jewish Hospital
  • 2004-2001: Chairman, Education Subcommittee, Barnes-Jewish Hospital Cancer Committee, Siteman Cancer Center
  • 2004-2000: Member, Education Subcommittee, Barnes-Jewish Hospital Cancer Committee

Board Certification

  • 2008, 1997: American Board of Internal Medicine (Medical Oncology)
  • 1996: American Board of Internal Medicine (Hematology)
  • 1993: American Board of Internal Medicine

Honors & Awards

  • 2020: AACR Team Science Award
  • 2016: Anheuser Busch Endowed Chair in Medical Oncology
  • 2016: Alton Ochsner Award Related Smoking and Disease
  • 2001: ASCO Clinical Research Career Development Award for research titled “A Pilot Study of Celecoxib in Patients with Barrett’s Esophagus”
  • 1993: Alfred Pick Award for academic excellence during the Internal Medicine Residency at Michael Reese Hospital and Medical Center, Chicago, IL

International & National Committee Memberships

  • present-2019: Member, PierianDx Knowledgebase Expert Panel
  • present-2019: Member, The Cancer Genoma Atlas Lung Adenocarcimona Subgroup (TCGA LUAD) NIH/NCI
  • present-2018: Member, AACR Lung Cancer Research Fellowships Scientific Review Committee
  • present-2018: Member, ALCHEMIST Core Committee
  • present-2018: Member, K12 External Advisory Committee
  • present-2018: Member, PDX Steering Committee
  • present-2018: Co-Chair, SITC Lung Subcommittee
  • present-2018: Member, SITC Cancer Immunotherapy Guidelines (CIG) Committee
  • present-2014: Member, SITC/Medscape CME Project Steering Committee
  • present-2014: Member, ALCHEMIST Champions Team
  • present-2013: Member, National Comprehensive Cancer Network (NCCN) National Cancer Institute (NCI) Non-Small Cell Lung Cancer Panel
  • present-2012: Chair, IASLC CME Subcommittee
  • present-2010: Co-Chair, Lung Cancer Disease Working Group, The Cancer Genome Atlas Project
  • present-2009: Member, Subcommittee H, NCI
  • present-2009: Member, IASLC Pathology Committee
  • present-2008: Member, Cancer Center Review Panel, NCI
  • present-2008: Member, American College of Surgical Oncology (ACOSOG)
  • present-2008: Member, Education Committee, ASCO
  • present-2007: Member, NCCN Guidelines Committee, Non-Small Cell Lung Cancer
  • present-2002: Member, Clinical Oncology Advisory Board (COAB)
  • present-2001: Member, Respiratory Core Committee, Cancer and Leukemia Group B (CALGB)
  • present-2000: Member, Lung Committee, Hoosier Oncology Group (HOG)
  • present-2000: Member, Lung Steering Committee, Radiation Therapy Oncology Group (RTOG)
  • 2019: Member, Dr. Dubinett’s CLIN2-10784 Clinical Advisory Panel
  • 2014: Member, International Association for the Study of Lung Cancer Core Program Committee for the Treatment of Localized Disease NSCLC Track
  • 2010: Member (ad hoc), NCI Basic, Translational and Clinical Oncology Special Emphasis Panel
  • 2009: Member, Review Panel, American Recovery Reinvestment Act (ARRA)
  • 2008-2007: Member (ad hoc), NCI SPORE Review Panel
  • 2007-2005: Chair, Lung Committee (P2C-Mayo Consortium)
  • 2007-2000: Co-Chair, Lung Committee, Hoosier Oncology Group (HOG)
  • 2006-2004: Member, Lung Cancer Program Committee, American Society of Clinical Oncology
  • 2005-2002: Vice-Chair, Midwest Oncology Group (MOG)
  • 2003: Reviewer for Cancer Research UK (formerly ICRS and CRC) Phase I and II protocols
  • 2001-1998: Member, Oncology Training Program Committee, American Society of Clinical Oncology (ASCO)
  • 2000: Member, Quality Assurance Subcommittee, Radiation Therapy Oncology Group (RTOG)
  • 2009: Vice Chair, Medical Oncology Committee, American College of Surgical Oncology (ACOSOG)

Editorial Responsibilities

  • present-2010: Cancer Pharmacology, Lippincott, Williams & Wilkins
  • present-2010: Oncology Advisory Editor, Oncology Times
  • present-2009: Clinical Care Options InPractice Oncology
  • present-2008: Proceedings of the Annual Targeted Therapy Meeting Summary, International Association for the Study of Lung Cancer (ISLAC)
  • present-1999: ASCO Training Program Committee, Reading Syllabus on ASCO website
  • 2015: Washington Manual of Oncology, 3rd Edition, Lippincott, Williams & Wilkins Contemporary Oncology (bi-weekly newsletter/journal), Lippincott, Williams & Wilkins, Co-editor: Michael C. Perry
    Thoracic Oncology Matters (quarterly), Washington University School of Medicine
  • 2011-2008: ASCO Meeting Summaries
  • 2011-2006: ASCO Educational Book
  • 2009: DeVita, Hellman & Rosenberg’s “Cancer, Principles & Practice of Oncology Review” 2nd Edition, Lippincott Williams & Wilkins
  • 2009: Lung Cancer, Monograph, Lippincott, Williams & Wilkins
  • 2008: E-Update Series- Non-small Cell Lung Cancer, CMP Media
  • 2007: Washington Manual of Oncology, 2nd Edition, Lippincott, Williams & Wilkins
  • 2007: E-Update Series- Non-small Cell Lung Cancer, CMP Media
  • 2006: Locally Advanced Non-Small-Cell Lung Cancer: Cancer Management: a Multidisciplinary Approach, CMP United Business Media/Publishers of Oncology
  • 2005: DeVita, Hellman & Rosenberg’s “Cancer, Principles & Practice of Oncology Review”, Lippincott Williams & Wilkins
  • 2004: Locally Advanced Non-small Cell Lung Cancer: A Practical Management Guide, a COAB publication
  • 2002: Washington Manual of Oncology, Lippincott, Williams & Wilkins